Metabolic basis to Sherpa altitude adaptation


Nepalese Sherpas have a physiology that uses oxygen more efficiently than those used to the atmosphere at sea level. The biochemical tests on the fresh muscle showed that the Sherpas’ tissue was able to make much better use of oxygen by limiting the amount of body fat burned (i.e. low levels of fatty acid oxidation)…

Lecture Series on – “Conservation Biology and Wildlife Genetics in Nepal”


8 lecture series on the theme “Conservation Biology and Wildlife Genetics in Nepal” was held at Kathmandu University. The lecture series was given by Prof Dr Jacques Van Alphen (University of Amsterdam) and Dr Laura Bertola (Leiden University) and was jointly organized by Himalayan Tiger Foundations and Center for Molecular Dynamics Nepal (CMDN). (24-25 Nov…

The BARCODE Data Standards


Following is a presentation byDavid Schindel discussing on the current standards in BARCODE data flag in GenBank and some of the burning issues in Species Name assignment across the database repository systems. It was presented in the recent “Fourth International Barcode of Life Conference” held at The University of  Adelaide, Australia from 28 Nov –…

Front-end processing of DNA Barcoding


Here is a presentation by Michelle Van der Bank discussing on Front-end processing of DNA Barcoding. The presentation roams around Specimen arraying, imaging, sampling. Pre-lab challenges and solutions: individual tracking of collection specimens, avoiding human error when working with large batches of specimens, streamlining front-end processing of large specimen batches and issues regarding the DNA Barcode data…

Age-dependent expression of Housekeeping genes


Housekeeping genes are a set of genes that is constitutively expressed irrespective of the tissue type in a genome (Eisenberg and Levanon, 2003).  Housekeeping genes are more important in any gene-expression or qPCR analysis and is often considered as standards to quantify gene-expression. It’s generally believed that certain housekeeping genes are always expressed at more-or-less…